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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K7 All Species: 16.97
Human Site: T466 Identified Species: 33.94
UniProt: O43318 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43318 NP_003179.1 606 67196 T466 S P S V R M I T T S G P T S E
Chimpanzee Pan troglodytes XP_001160138 472 51727 T344 Q V P A T N D T I K R L E S K
Rhesus Macaque Macaca mulatta XP_001099744 609 67549 R466 R S S S P S V R M I T T S G P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q62073 579 64209 T439 S P S V R M I T T S G P T S E
Rat Rattus norvegicus P0C8E4 606 67182 T466 S P S V R M I T T S G P T S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507638 595 66386 T455 S P S V R M I T T S G P T S E
Chicken Gallus gallus XP_001233491 604 67342 S456 Q S R N S S R S S S P S V R M
Frog Xenopus laevis Q7T2V3 1005 111856 P607 A P N L G K S P K H T P I S V
Zebra Danio Brachydanio rerio NP_001018586 544 61104 P415 N N S R S S S P S F R M I T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3Q6 678 75656 R449 T N A K S D G R E R L T V T D
Honey Bee Apis mellifera XP_397248 510 58111 T382 S I L K I K N T T Q S N S T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795629 463 51420 N335 P H P S P L S N H Q Q P S T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.4 99.5 N.A. N.A. 95 99 N.A. 91.4 91.7 21.9 70.6 N.A. 34.5 41.4 N.A. 39.9
Protein Similarity: 100 75.7 99.5 N.A. N.A. 95 99.3 N.A. 93.7 93.7 35.7 77.8 N.A. 52.2 58.7 N.A. 51.4
P-Site Identity: 100 13.3 6.6 N.A. N.A. 100 100 N.A. 100 6.6 20 6.6 N.A. 0 20 N.A. 6.6
P-Site Similarity: 100 20 20 N.A. N.A. 100 100 N.A. 100 20 40 26.6 N.A. 26.6 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 9 0 0 0 34 0 0 9 0 % G
% His: 0 9 0 0 0 0 0 0 9 9 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 0 34 0 9 9 0 0 17 0 0 % I
% Lys: 0 0 0 17 0 17 0 0 9 9 0 0 0 0 9 % K
% Leu: 0 0 9 9 0 9 0 0 0 0 9 9 0 0 0 % L
% Met: 0 0 0 0 0 34 0 0 9 0 0 9 0 0 9 % M
% Asn: 9 17 9 9 0 9 9 9 0 0 0 9 0 0 0 % N
% Pro: 9 42 17 0 17 0 0 17 0 0 9 50 0 0 25 % P
% Gln: 17 0 0 0 0 0 0 0 0 17 9 0 0 0 0 % Q
% Arg: 9 0 9 9 34 0 9 17 0 9 17 0 0 9 0 % R
% Ser: 42 17 50 17 25 25 25 9 17 42 9 9 25 50 0 % S
% Thr: 9 0 0 0 9 0 0 50 42 0 17 17 34 34 9 % T
% Val: 0 9 0 34 0 0 9 0 0 0 0 0 17 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _